Change in osmolarity of disodium cromoglycate solution and protection against exercise-induced bronchospasm in children with asthma
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چکیده
منابع مشابه
Change in osmolarity of disodium cromoglycate solution and protection against exercise-induced bronchospasm in children with asthma.
It has been suggested that osmolarity and/or nebulizer output may affect the protective effects of disodium cromoglycate (DSCG) in asthma. The aim of this study was to evaluate the influence of osmolarity of the DSCG solution on exercise-induced bronchospasm (EIB) in children with bronchial asthma. A jet nebulizer was used for DSCG inhalation in Study 1 and an ultrasonic nebulizer in Study 2. T...
متن کاملEffect of disodium cromoglycate on exercise-induced asthma.
In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.
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Ketotifen (Zaditen), a benzocycloheptathiophene derivative, is a new oral agent for treating asthma, with action similar in some respects to that of sodium cromoglycate. It is well established that sodium cromoglycate protects against antigen challenge by inhibiting the release of chemical mediators from mast cells. It also inhibits exerciseinduced bronchoconstriction and has bronchodilator pro...
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متن کاملExercise-induced bronchospasm in children.
This review will encompass definition, history, epidemiology, pathogenesis, diagnosis, and management of exercise -induced bronchospasm in the pediatric individual with and without known asthma. Exercise induced asthma is the conventional term for transient airway narrowing in a known asthma in association with strenuous exercise usually lasting 5-10 minutes with a decline in pulmonary function...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1996
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.96.09091891